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Shotgun engineering enables rapid metabolic design in mammalian cells

A new multiplexed strategy screens millions of combinatorial gene modifications to discover productive metabolic pathways for synthesizing essential amino acids.

1 publisher · 3 articles · first seen 6 Oct 2026 · updated 2d ago

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1 publisher has covered this in 3 articles since 6 Oct 2026. Nature Biotechnology published first, on 6 October at 00:00 UTC. The most recent article, from Nature Biotechnology, appeared on 6 October at 00:00 UTC.

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  1. Highly multiplexed mammalian metabolic engineering with a shotgun approach Nature Biotechnology ·
  2. High-throughput metabolic engineering in mammalian cells Nature Biotechnology ·
  3. Shotgun engineering fires up mammalian metabolic design Nature Biotechnology ·
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