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Prime assembly enables precise genomic integration without double-strand breaks

The technique allows RNA-guided insertion of large DNA sequences in human cells, supporting exon recoding and megabase-scale rearrangements.

2 publishers · 2 articles · first seen 16 Sept 2026 · updated 45d ago

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The story so far

2 publishers have covered this in 2 articles since 16 Sept 2026. Nature published first, on 16 September at 00:00 UTC; Spotlight news only followed 17h 20m later. The most recent article, from Spotlight news only, appeared on 16 September at 17:20 UTC.

Outlets reporting it: Nature (major outlet), Spotlight news only.

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Sources

Every article we clustered into this story. Headlines link to the publisher.

  1. Targeted genomic integration and rearrangement using prime assembly Nature ·
  2. Prime assembly can correct multiple mutations at once, pointing toward universal gene therapies Spotlight news only
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