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DHHC12 identified as key switch linking amino acid sensing to insulin secretion

Research shows DHHC12 degradation blocks SYT7 palmitoylation and insulin secretion, with human variants correlating to fasting glucose levels.

1 publisher · 1 article · first seen 12 Oct 2026 · updated 2d ago

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1 publisher has covered this in 1 article since 12 Oct 2026. Nature Communications published first, on 12 October at 00:00 UTC.

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  1. DHHC12 serves as a critical nutrient-responsive switch that couples amino acid sensing to insulin secretion Nature Communications ·

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